Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required) | PAR 23 170

Opportunity Information: Apply for PAR 23 170

This NIH funding opportunity (PAR-23-170) is an R01 grant focused on designing and testing practical, multi-level interventions that increase the use of cancer screening and related preventive services in populations that experience health disparities. Led by the NIH Office of Disease Prevention (ODP) in partnership with multiple NIH Institutes, Centers, and Offices, the program is aimed at closing persistent gaps in who gets screened, who receives preventive services, and who successfully completes follow-up care after abnormal results. A central premise of the announcement is that disparities are rarely driven by a single factor, so proposed projects are expected to tackle real-world barriers and facilitators operating across at least two levels of influence: the patient level, clinician level, healthcare setting level, and neighborhood/community level.

The research supported under this opportunity is not limited to simply increasing initial screening rates. Applicants are encouraged to address the full continuum of screening and prevention-related care, including the processes that often break down for underserved groups. This includes timely follow-up of abnormal findings, coordination and navigation support, and referrals to accessible diagnostic and treatment services when needed. In other words, the emphasis is on improving completion and quality of care pathways, not just getting someone to the first step. The NIH also highlights the value of partnering with community organizations and service providers, reflecting an expectation that strong applications will be grounded in the realities of local health systems and community contexts, and will leverage trusted partnerships to improve reach, uptake, and sustainability.

Because this is an R01 with a Clinical Trial Required designation, applications should include rigorous testing of an intervention where participants are prospectively assigned to receive one or more interventions (or comparison conditions) in order to evaluate effects on health-related biomedical or behavioral outcomes. The intervention focus can involve screening and preventive services broadly, but the core requirement is that the proposal includes a trial structure appropriate to the research question and the populations being served. The announcement notes that specific research interests vary across the participating NIH components and are described within the full funding opportunity, meaning applicants should align their aims and methods with the priorities of the relevant NIH Institute or Center.

Eligibility is broad and includes many types of domestic organizations and governmental entities. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits with or without 501(c)(3) status (other than institutions of higher education); public housing authorities/Indian housing authorities; Native American tribal governments (federally recognized); Native American tribal organizations (other than federally recognized tribal governments); for-profit organizations other than small businesses; and small businesses. The announcement also explicitly encourages or recognizes additional eligible applicants such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), as well as faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. At the same time, it places clear limits on foreign involvement: non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply, although foreign components as defined by the NIH Grants Policy Statement are allowed.

Administratively, the opportunity is offered by the National Institutes of Health as a discretionary grant mechanism under the health and education-related funding activity categories, with CFDA numbers listed as 93.121, 93.307, 93.313, and 93.399. The funding opportunity was created on April 19, 2023, and the listed original closing date is January 7, 2027. Overall, the program is geared toward teams that can combine implementation-aware trial designs, multi-level intervention strategies, and meaningful community/healthcare partnerships to improve equitable access to cancer screening, prevention services, and the follow-up care needed to translate screening into better outcomes.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.307, 93.313, 93.399.
• This funding opportunity was created on 2023-04-19.
• Applicants must submit their applications by 2027-01-07.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 23 170

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